The EGEE project officially ended on the 31 March 2006
EGEE II started on 1 April 2006 and the new EGEE website can be found at:
http://www.eu-egee.org
Biomedical Applications
Pilot applications in the Biomedical area have been included in the EGEE project since the beginning. Ten regularly used
applications are now available and several new initiatives are currently being investigated.
The WISDOM Drug Discovery application aims to help speed up the process of finding new drugs against malaria (the world's second biggest killer after tuberculosis). The Application was deployed and led to the most compute-intensive Data Challenge attempted on the EGEE Grid Production Service in the biomedical application field. The large scale 'in silico'
docking computation performed provided results on the probability for a given set of chemical compunds to dock on a target active protein.
Other Biomedical Applications that are using the EGEE Production service are as follows:
GATE (Geant4 Application for Tomographic Emission) - is a radio therapy planning
and medical tomography application.
GPS@ (Grid protein Sequence @nalysis) - is a bioinformatic portal dedicated to various protein analysis tools, running on the Grid in order to be able to help biologists and physicians understand the genomes which have now been sequenced.
CDSS (Clinical Decisions Support System) is an application aimed at helping practitioners and other medical staff make more informed decisions as to the best way to treat a condition.
Docking Platform for Tropical Diseases drug discovery application aims to help speed up the hunt for new drugs to combat neglected diseases.
gPTM3D is a grid method of collecting, producing and analysing three-
dimensional images of human organs to aid surgeons in the diagnosis of such things as cancer.
SiMRI3D is a parallel MRI simulator, producing 3D images of medical scans.
Xmipp_MLrefine is an application which cleans up
Electron Microscopic images of molecular structures.
GridGRAMM is an application which enables molecular docking analysis, and is intended
to develop into an anonymous useable generic portal for this type of analysis.
GROCK (Grid Dock) enables mass screening of molecular interactions.
There are also four more biomedical applications currently being tested, which will soon be ready for porting to the Production
service;
SPLATCHE (SPatiaL And Temporal Coalescences in Heterogeneous Environment) is a
life science application which is designed to analyse the predicted movement of humans in a known geographic area, analysing past human movement and reconstructing historical demographics to generate the molecular diversity of a gene taken from any point in the simulation to measure human genetic development.
Bronze Standards is an attempt to benchmark known images using complicated algorithms, which would be impossible on a single PC due to the size of the data bases involved.
Xmipp_assign_multiple_CTFs (Micrographia Contrast Transfer Function calculation) is an application cleaning up another aspect of electron microscopic images, taking into account the 'Contrast Transfer Function' (CTF) which is a known variance of electron microscopes.
Pharmacokinetics is a liver contrast agent diffusion study application based on abdominal MRI registrations.
Please feel free to visit the individual application's website for a more in depth analysis of their activities.